Paper I
2024 December (Supplementary) (2019 Scheme) · 100 marks · 180 min

Question

Recurrence of such episodes as in this case can be prevented by prophylaxis with

  • a) Vancomycin
  • b) Methicillin
  • c) Cloxacillin
  • d) Penicillin
Qiv1 marksMCQs

Answer

- [x] d) Penicillin

Penicillin (given as long-acting benzathine penicillin G intramuscularly, typically every 3–4 weeks, or oral penicillin V) is the standard agent for secondary prophylaxis against recurrent Streptococcus pyogenes infection in patients with rheumatic fever/rheumatic heart disease, preventing further streptococcal-triggered immune-mediated cardiac damage. Vancomycin, methicillin, and cloxacillin are anti-staphylococcal agents, not the standard choice for streptococcal secondary prophylaxis in rheumatic heart disease.

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