Paper I — 2025 March (Supplementary (SAY)) (2019 Scheme) — Qii

Paper I

2025 March (Supplementary (SAY)) (2019 Scheme) · 100 marks · 180 min

Question

Which of the following is important for diagnosis

• a) Same pathogen isolated from 3 blood culture samples
• c) Antibodies to Rheumatoid factor
• b) Antibodies to Antistreptolysin O
• d) High levels of troponin

Qii1 marksMCQs★✓

Answer

- [x] a) Same pathogen isolated from 3 blood culture samples

Persistently positive blood cultures — specifically, isolation of a typical infective-endocarditis-causing organism from at least two/three separate blood culture samples (or persistently positive cultures drawn 12 hours apart) — is one of the major criteria of the Modified Duke criteria for diagnosing infective endocarditis, reflecting sustained bacteraemia arising from the intracardiac vegetation. Antistreptolysin O antibodies and rheumatoid factor are relevant to other conditions (rheumatic fever and rheumatoid arthritis, respectively) rather than being diagnostic criteria for infective endocarditis, and while elevated troponin can reflect myocardial involvement, it is a non-specific finding, not part of the Duke diagnostic criteria.

Related Concepts

1. 1Rheumatic Fever

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