Paper II
2025 March (Supplementary (SAY)) (2019 Scheme) · 100 marks · 180 min

Question

Which anti-diarrhoeal drug acts by inhibiting intestinal motility via opioid receptors

  • a) Loperamide
  • b) Bismuth subsalicylate
  • c) Dicyclomine
  • d) Mesalamine
Qi1 marksMCQs

Answer

Correct answer: a) Loperamide

Loperamide is an opioid-receptor agonist, peripherally restricted (minimal CNS penetration at normal doses), that reduces intestinal peristalsis and increases transit time, producing an antimotility antidiarrheal effect.

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