Paper II — 2024 December (Supplementary) (2019 Scheme) — Qxv
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Paper II
2024 December (Supplementary) (2019 Scheme) · 100 marks · 180 min
Question
(A) Osteoarthritis is a chronic inflammatory disease of autoimmune origin.
(R) It is an intrinsic disorder of cartilage in response to mechanical and biochemical stress and failure of
its repair
a) Both A & R are correct and R is the reason for A
b) Both A & R are correct but R is not reason for A
c) A is correct R is incorrect
d) A is incorrect R is correct
Question numbers (xvi) – (xx) Read the following case scenario and answer subsequent questions
based on this
A 53-year-old man has experienced severe chest pain for the past 6 hours. On physical examination he is
afebrile, but has tachycardia. Laboratory studies show a serum troponin I of 10 ng/mL. A coronary angiogram
is performed emergently and reveals >90% occlusion of the anterior interventricular (left anterior descending)
artery.
Qxv1 marksMCQs
Answer
Correct answer: d) A is incorrect R is correct
Question numbers (xvi) – (xx) Read the following case scenario and answer subsequent questions
based on this
A 53-year-old man has experienced severe chest pain for the past 6 hours. On physical examination he is
afebrile, but has tachycardia. Laboratory studies show a serum troponin I of 10 ng/mL. A coronary angiogram
is performed emergently and reveals >90% occlusion of the anterior interventricular (left anterior descending)
artery.
Assertion (A) is incorrect — osteoarthritis is not a chronic inflammatory disease of autoimmune origin (that description fits rheumatoid arthritis); osteoarthritis is a degenerative joint disease. Reason (R) is correct — osteoarthritis is fundamentally an intrinsic disorder of articular cartilage, arising from cumulative mechanical and biochemical stress on the joint combined with failure of the chondrocytes’ normal repair mechanisms, leading to progressive cartilage breakdown.
