Paper I — 2025 March (Supplementary) (2010 Scheme) — Q16

Paper I

2025 March (Supplementary) (2010 Scheme) · 40 marks · 120 min

Question

Selective serotonin reuptake inhibitors.

Q160.3 marksShort Answers★✓

Answer

Fluoxetine, Sertraline (also Escitalopram, Paroxetine) — selectively inhibit presynaptic serotonin reuptake, raising synaptic serotonin availability; first-line for major depressive disorder and anxiety disorders.

Related Concepts

1. 1Antidepressants and Antianxiety Drugs

Other Years Asked

1. 1A 29-year employee gradually stopped going out, withdrew socially. He felt guilty, worthless and tired all time, lost interest in pleasure and sex and had disturbed sleep. Physician diagnosed him a case of Major depression. (2023 July (Supplementary) (2019 Scheme)Essay · 15 marks
2. 2A 25-year-old male with symptom of excessive fatigue and lack of sleep was brought to the clinic. His relatives say that he is socially withdrawn and has made two attempts of suicide. He was prescribed tab fluoxetine.  Explain the mechanism of action, uses and adverse effects of fluoxetine.  Classify other drugs useful in the above condition. (3+3)2023 July (Supplementary) (2010 Scheme)Essay · 6 marks
3. 3day for her. Answer the following:  What is the mechanism of action of fluoxetine.  What is the advantage of this drug compared to tricyclic antidepressants.  What can happen if this patient is administered pethidine concurrently (2+2+2)2018 February (2010 Scheme)Essay · 6 marks
4. 4Mention SSRI and its advantages.2014 September (Supplementary) (2010 Scheme)Short Note · 3 marks
5. 5Selective serotonin reuptake inhibitors2014 March (2010 Scheme)Short Note · 3 marks
6. 6Selective serotonin reuptake inhibitors2021 May (Supplementary) (2010 Scheme)Short Note · 3 marks
7. 7Sertraline.2025 August (Supplementary) (2010 Scheme)Short Note · 3 marks
8. 8Selective serotonin reuptake inhibitors2021 February (Supplementary) (2010 Scheme)Short Note · 3 marks
9. 9Selective serotonin reuptake inhibitors2017 August (Supplementary) (2010 Scheme)Short Answer · 1 mark
10. 10Selective serotonin reuptake inhibitors2017 February (2010 Scheme)Short Answer · 1 mark
11. 11Fluoxetine2024 August (Supplementary) (2010 Scheme)Short Answer · 1 mark
12. 12Selective serotonin reuptake inhibitors (SSRI)2018 July (Supplementary) (2010 Scheme)Short Answer · 1 mark
13. 13Selective serotonin reuptake inhibitors2022 October (Supplementary) (2010 Scheme)Short Answer · 1 mark
14. 14Amitriptyline2020 February (Supplementary) (2010 Scheme)Short Answer · 1 mark
15. 15Selective serotonin reuptake inhibitor2019 February (2010 Scheme)Short Answer · 0.3 marks