Paper I — 2019 February (2010 Scheme) — Q20

Paper I

2019 February (2010 Scheme) · 40 marks · 120 min

Question

Selective serotonin reuptake inhibitor

Q200.3 marksShort Answers★✓

Answer

Fluoxetine — selectively inhibits presynaptic reuptake of serotonin, increasing synaptic 5-HT availability, making it effective and well-tolerated first-line therapy for major depressive disorder with a much safer overdose profile than tricyclic antidepressants.

Related Concepts

1. 1Antidepressants and Antianxiety Drugs

Other Years Asked

1. 1A 29-year employee gradually stopped going out, withdrew socially. He felt guilty, worthless and tired all time, lost interest in pleasure and sex and had disturbed sleep. Physician diagnosed him a case of Major depression. (2023 July (Supplementary) (2019 Scheme)Essay · 15 marks
2. 2A 25-year-old male with symptom of excessive fatigue and lack of sleep was brought to the clinic. His relatives say that he is socially withdrawn and has made two attempts of suicide. He was prescribed tab fluoxetine.  Explain the mechanism of action, uses and adverse effects of fluoxetine.  Classify other drugs useful in the above condition. (3+3)2023 July (Supplementary) (2010 Scheme)Essay · 6 marks
3. 3day for her. Answer the following:  What is the mechanism of action of fluoxetine.  What is the advantage of this drug compared to tricyclic antidepressants.  What can happen if this patient is administered pethidine concurrently (2+2+2)2018 February (2010 Scheme)Essay · 6 marks
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