Paper I — 2025 March (Supplementary) (2010 Scheme) — Q13

Paper I

2025 March (Supplementary) (2010 Scheme) · 40 marks · 120 min

Question

Clozapine.

Q131 marksShort Answers★✓

Answer

Uses: Treatment-resistant schizophrenia (failed at least two other antipsychotics); Reduction of suicidal behaviour in schizophrenia

Adverse effects: Agranulocytosis (requires mandatory regular blood count monitoring); Weight gain and metabolic disturbance (most pronounced among the atypicals)

Related Concepts

1. 1Antipsychotic and Antimanic Drugs

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