Paper II — 2025 March (Supplementary) (2010 Scheme) — Q4

Paper II

2025 March (Supplementary) (2010 Scheme) · 40 marks · 120 min

Question

Name TWO pathogenic free living amoeba and the infection caused by each of them

Q42 marksShort Notes★✓

Answer

Two pathogenic free-living amoebae and the infection each causes:

1. Naegleria fowleri — causes Primary Amoebic Meningoencephalitis (PAM), a rare but almost universally fatal, rapidly progressive CNS infection in previously healthy individuals, acquired via nasal exposure to contaminated warm freshwater.
2. Acanthamoeba species — cause Granulomatous Amoebic Encephalitis (GAE), a chronic CNS infection predominantly in the immunocompromised, and Acanthamoeba keratitis, a serious corneal infection strongly associated with contact lens wear.

(Other valid example: Balamuthia mandrillaris — causes a GAE-like chronic encephalitis.)

Related Concepts

1. 1Primary Amoebic Meningoencephalitis and Granulomatous Amoebic Encephalitis

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