Revise MBBS

Paper II — 2022 February (2019 Scheme) — Q21

2 min read

Paper II
2022 February (2019 Scheme) · 100 marks · 180 min

Question

Epidermal growth factor receptor inhibitors

Q210.2 marksShort Answers

Answer

Erlotinib, Gefitinib — small-molecule tyrosine kinase inhibitors targeting the EGFR intracellular domain, blocking downstream proliferative signaling; used in EGFR-mutant non-small-cell lung cancer.

  1. 1Pharmacodynamics

Other Years Asked

  1. 1Define a receptor. Discuss the various transducer mechanisms by which the receptors act. (1+5)2018 July (Supplementary) (2010 Scheme)Essay · 6 marks
  2. 2Drug antagonism.2025 August (Supplementary) (2010 Scheme)Short Note · 3 marks
  3. 3Drug antagonism.2015 February (2010 Scheme)Short Note · 3 marks
  4. 4Drug Antagonism2023 July (Supplementary) (2010 Scheme)Short Note · 3 marks
  5. 5Drug antagonism2021 May (Supplementary) (2010 Scheme)Short Note · 3 marks
  6. 6Drug antagonism2017 February (2010 Scheme)Short Note · 3 marks
  7. 7G-protein coupled receptors2020 February (Supplementary) (2010 Scheme)Short Note · 3 marks
  8. 8Assertion (A): Allopurinol can precipitate acute gout. Reason (R): Inhibition of uric acid synthesis mobilizes tissue store of uric acid in to plasma.2025 March (Supplementary (SAY)) (2019 Scheme)MCQ (A/R) · 1 mark
  9. 9Assertion (A): Propranolol is often used to manage symptoms of hyperthyroidism. Reason (R): Propranolol is a non-selective beta-blocker that reduces the symptoms of hyperthyroidism by blocking the effects of excessive thyroid hormones on the heart.2025 March (Supplementary (SAY)) (2019 Scheme)MCQ (A/R) · 1 mark
  10. 10Drug induced parkinsonism2013 April (2010 Scheme)Short Answer · 1 mark
  11. 11Dimercaprol2022 May (Supplementary) (2010 Scheme)Short Answer · 1 mark
  12. 12Assertion (A): Beta-2 agonists, such as salbutamol, are used to treat asthma. Reason (R): Beta-2 agonists work by stimulating beta-2 adrenergic receptors on bronchial smooth muscles, causing bronchodilation.2025 March (Supplementary (SAY)) (2019 Scheme)MCQ (A/R) · 1 mark
  13. 13Substances that precipitate superficial surface proteins without penetrating the cells and toughen the skin making it mechanically stronger and decrease exudation are called:2024 December (Supplementary) (2019 Scheme)MCQ · 1 mark
  14. 14Disease modifying anti-rheumatic drugs2018 February (2010 Scheme)Short Answer · 1 mark
  15. 15Potassium channel openers2021 May (Supplementary) (2010 Scheme)Short Answer · 0.3 marks
  16. 16Potassium channel openers2021 December (Supplementary) (2010 Scheme)Short Answer · 0.3 marks

Graph View

Revise MBBS
Preview