Paper I
2025 March (Supplementary (SAY)) (2019 Scheme) · 100 marks · 180 min

Question

The most common cause for male hypogonadism is

  • a) Klinefelter’s syndrome
  • b) Turner’s syndrome
  • c) Down’s syndrome
  • d) Edward’s syndrome
Qiv1 marksMCQs

Answer

Correct answer: a) Klinefelter’s syndrome

Klinefelter syndrome (47,XXY) is the most common cause of male hypogonadism/infertility due to a chromosomal abnormality — testicular dysgenesis from the extra X chromosome causes hypergonadotropic hypogonadism. (Turner syndrome affects females; Down and Edward syndromes are autosomal trisomies not primarily associated with hypogonadism as their defining feature.)

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