Question
Lab diagnosis of dengue fever
Q62 marksShort Notes
Answer
Laboratory diagnosis of dengue fever (Dengue virus, a Flavivirus):
- NS1 antigen — detectable from day 1, before antibody develops, useful for early diagnosis.
- IgM ELISA — becomes positive from about day 5 of illness, indicating recent infection.
- IgG ELISA — the IgM:IgG pattern helps distinguish primary from secondary infection.
- RT-PCR — detects viral RNA in the early viraemic phase, allows serotyping.
- Full blood count — thrombocytopenia and rising haematocrit (haemoconcentration, reflecting plasma leakage) are key supportive findings.
- Tourniquet test — a simple bedside test for capillary fragility, supporting the diagnosis of haemorrhagic tendency.
- 1Dengue Fever and Viral Haemorrhagic Fever
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maculopapular rash, pain in the back and limbs for the past ten days. The fever is
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What is the probable diagnosis and the causative agent
How the disease is transmitted. Name two other diseases transmitted in the
same way.
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- 10Viral haemorrhagic fever.2016 February (2010 Scheme)Short Note · 2 marks
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