Paper I
Question
Which of the following mediators suppress inflammation
Answer
Correct answer: d) Lipoxin
Lipoxins are anti-inflammatory arachidonic acid derivatives that actively suppress/resolve inflammation — they inhibit neutrophil chemotaxis and adhesion, and promote the resolution phase of the inflammatory response. In contrast, prostaglandins, prostacyclin, and leukotrienes are generally pro-inflammatory mediators (though prostacyclin is also a vasodilator/antiplatelet agent, it is not classically an anti-inflammatory “stop signal” mediator in the way lipoxins are).