Paper II — 2023 July (Supplementary) (2010 Scheme) — Q16

Paper II

2023 July (Supplementary) (2010 Scheme)

Question

Drugs used for Lepra reaction

Q160.3 marksShort Answers★✓

Answer

Corticosteroids, Thalidomide — corticosteroids treat Type 1 (reversal) reactions, urgently preserving nerve function; thalidomide is specifically effective for Type 2 reactions (erythema nodosum leprosum) via its immunomodulatory/anti-TNF-alpha property, though contraindicated in women of childbearing potential given its severe teratogenicity.

Related Concepts

1. 1Antileprotic Drugs

Other Years Asked

1. 1(2023 July (Supplementary) (2019 Scheme)Short Essay · 8 marks
2. 2Thalidomide2018 February (2010 Scheme)Short Note · 3 marks
3. 3Lepra reaction2015 February (2010 Scheme)Short Note · 3 marks
4. 4Multi bacillary leprosy.2013 September (Supplementary) (2010 Scheme)Short Answer · 1 mark
5. 5Clofazimine2019 July (Supplementary) (2010 Scheme)Short Answer · 1 mark
6. 6Lepra reactions2013 April (2010 Scheme)Short Answer · 1 mark
7. 7Pharmacological basis for the use of thalidomide in lepra reaction2017 August (Supplementary) (2010 Scheme)Short Answer · 1 mark
8. 8Uses of clofazimine2016 February (2010 Scheme)Short Answer · 1 mark
9. 9Drugs useful in Lepra reaction.2019 July (Supplementary) (2010 Scheme)Short Answer · 0.3 marks
10. 10Drugs for treating Lepra reaction2024 March (Supplementary) (2019 Scheme)Short Answer · 0.2 marks
11. 11Antileprotic drugs.2023 January (Supplementary) (2019 Scheme)Short Answer · 0.2 marks