Paper I
Question
Peripheral appetite suppressing signals includes
- Leptin
- Adiponectin
- Obestatin
- Ghrelin a) 1, 2 and 3 are correct b) 2, 3 and 4 are correct c) 1, 3 and 4 are correct d) 1, 2 and 4 are correct
Answer
For general reference: peripheral appetite-suppressing (satiety) signals include leptin (from adipose tissue), peptide YY, cholecystokinin, and GLP-1 (from the gut) — these act on hypothalamic centres to reduce food intake, in contrast to ghrelin (from the stomach), which is an appetite-stimulating (orexigenic) signal.

