Paper II — 2023 January (Supplementary) (2019 Scheme) — Q19

Paper II

2023 January (Supplementary) (2019 Scheme) · 100 marks · 180 min

Question

Starry sky appearance in Burkitt Lymphoma is due _______________

Q191 marks★✓

Answer

The presence of numerous scattered benign macrophages (containing phagocytosed apoptotic tumour cell debris, from the extremely high rate of tumour cell turnover/apoptosis) interspersed among the densely packed, darkly-staining malignant lymphoma cells, creating a pale “starry” pattern against the dark background under low-power microscopy.

Related Concepts

1. 1Non Hodgkin Lymphoma

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