Paper II — 2025 March (Supplementary (SAY)) (2019 Scheme) — Qxv

Paper II

2025 March (Supplementary (SAY)) (2019 Scheme) · 100 marks · 180 min

Question

(A) Charcot Leyden Crystals are seen in sputum of patients with Bronchial Asthma (R) Remodeling of the bronchial wall occurs in cases of Bronchial Asthma

• a) Both A & R are correct and R is the reason for A
• c) A is correct R is incorrect
• b) Both A & R are correct but R is not reason for A
• d) A is incorrect R is correct Question numbers (xvi) – (xx) Read the following case scenario and answer subsequent questions based on this A 58 year old female presented the surgical OPD with a lump in her right breast – 3 weeks. No pain or sudden increase in size O/E Solitary, ill-defined firm to hard nodular mass in the outer upper quadrant of breast. Examination of right axillary region shows four palpable nodes. contralateral breast is normal.

Qxv1 marksMCQs★✓

Answer

Correct answer: b) Both A & R are correct but R is not reason for A

Both statements are correct, but R is not the reason for A. Charcot-Leyden crystals (hexagonal, needle-shaped crystals formed from the breakdown of eosinophil granule protein, lysophospholipase/galectin-10) are indeed seen in the sputum of bronchial asthma patients (A is true). Airway remodeling (subepithelial fibrosis, smooth muscle hypertrophy, mucous gland hyperplasia) does occur in chronic bronchial asthma (R is also true). However, R does not explain A — Charcot-Leyden crystal formation results from eosinophil degranulation in the airway lumen, an independent process from the structural airway remodeling described in R.

Related Concepts

1. 1Bronchial Asthma