Paper I — 2024 December (Supplementary) (2019 Scheme) — Q15

Paper I

2024 December (Supplementary) (2019 Scheme) · 100 marks · 180 min

Question

Define Fever of Unknown Origin (FUO). List six causes of FUO commonly seen in India. (1+3)

Q154 marksShort Answers★✓

Answer

Definition: Fever of Unknown Origin (FUO), classically defined (Petersdorf and Beeson criteria), is a fever of ≥38.3°C (101°F) on several occasions, persisting for at least 3 weeks, with no diagnosis reached despite one week of intensive in-hospital (or equivalent outpatient) investigation.

Six causes of FUO commonly seen in India:

1. Tuberculosis (including extrapulmonary forms) — the single most important cause in the Indian context.
2. Enteric (typhoid) fever.
3. Malaria.
4. Visceral leishmaniasis (kala-azar).
5. Infective endocarditis.
6. Lymphoma (and other malignancies, an important non-infectious cause).

(Other valid examples: brucellosis; connective tissue/autoimmune disease, e.g., SLE; amoebic liver abscess; enteric fever relapse/carrier state; HIV-related opportunistic infection.)

Related Concepts

1. 1Normal Microbial Flora, PUO and Water Milk Bacteriology

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