Paper I
Question
Modafinil in night shift workers
Answer
Modafinil is a wakefulness-promoting agent that acts on the hypothalamic sleep-wake centres (mechanism not fully elucidated, but distinct from classical amphetamine-like stimulants, with lower abuse potential). It is used to counter excessive sleepiness and improve alertness in individuals with shift-work sleep disorder, helping night-shift workers maintain wakefulness and performance during their working hours when their natural circadian rhythm favours sleep.