Paper II — 2024 June (Supplementary) (2019 Scheme) — Q21

Paper II

2024 June (Supplementary) (2019 Scheme) · 100 marks · 180 min

Question

Name the antibody seen in Goodpasture syndrome

Q211 marks★✓

Answer

Anti-glomerular basement membrane (anti-GBM) antibody — an autoantibody directed against the α3 chain of type IV collagen, targeting both the glomerular and alveolar basement membranes in Goodpasture syndrome, producing a characteristic linear immunofluorescence pattern.

Related Concepts

1. 1Primary Glomerulonephritis

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