Paper II
Question
(A) Migratory thrombophlebitis occurs in 10% of pancreatic carcinomas (R) Pancreatic carcinomas are associated with platelet aggregating factors, anticoagulants and necrotic products.
Answer
Correct answer: a) Both A & R are correct and R is the reason for A
Both statements are correct, and R explains A. Migratory thrombophlebitis (Trousseau sign/syndrome) occurs in roughly 10% of patients with pancreatic carcinoma. This paraneoplastic hypercoagulable state is caused by tumour release of platelet-aggregating factors, mucins, and procoagulant/necrotic tumour products that activate the clotting cascade, directly explaining the tendency toward recurrent, migratory venous thromboses seen in A.